One man's swordfish story: The link between Alzheimer's disease and mercury exposure.
One man's swordfish story: The link between Alzheimer's disease and mercury exposure. Complement Ther Med. 2020 Aug;52:102499 Authors: Foley MM, Seidel I, Sevier J, Wendt J, Kogan M Abstract It is well-documented that when mercury levels surpass the permissible value, individuals experience a myriad of symptoms that include chronic fatigue, dizziness, and loss of appetite. Mercury is also known to be one of the most potent neurotoxins. This case study depicts a 91- year-old who presented with cognitive decline diagnosed as Alzheimer's disease. This patient was found to have severely elevated mercury levels caused by consuming high mercury containing fish. Following diet adjustment and detoxification, this patient's cognitive impairment significantly improved in proportion to the decline in methylmercury level. One year later, his cognition and functional status rapidly and unexpectedly declined. A computed tomography (CT) scan revealed multiple new lacunar subacute strokes. Thus, it is critical to address biological etiologies such as mercury toxicity in the elderly population diagnosed with Alzheimer's, but end organ damage may not be reversible. PMID: 32951747 [PubMed - in process]
Background Cognitive impairment is prevalent in heart failure and is associated with higher mortality rates. The mechanism behind cognitive impairment in heart failure with preserved ejection fraction (HFpEF) has not been established. Objective The aim of this study was to evaluate associations between abnormal cardiac hemodynamics and cognitive impairment in individuals with HFpEF. Methods A secondary analysis of Atherosclerosis Risk in Communities (Atherosclerosis Risk in Communities) study data was performed. Participants free of stroke or dementia who completed in-person assessments at visit 5 were in...
POTASSIUM deficiency can be dangerous to treat with supplements, meaning that in order to treat the symptoms of deficiency you'll have to look at changing your diet.
The fasting mimicking diet is, in essence, a clever strategy to pull in significant funding for the rigorous study of the use of forms of calorie restriction as a therapy. A fasting mimicking diet involves taking in just few enough calories to trigger most of the benefits of fasting. There must exist a dividing line in calorie intake at which nutrient sensor mechanisms determine that the body is in a state of fasting. Early research into fasting mimicking found that dividing line to be somewhere in the vicinity of 500 to 750 calories daily, but later studies use lower calorie levels. Another important point of calibration ...
HIGH blood pressure, also known as hypertension, can hike your risk of heart disease so it's vital to build defensive barriers against it. Diet holds the key here and a "blue" juice has been shown to lower systolic blood pressure over the course of a week.
THE THREAT of stroke continues to loom large as health services struggle to come to grips with Covid disruptions. Thankfully, the condition is highly preventable. New research has unearthed a key trigger that could increase the risk of stroke by 30 percent.
The diet lowers the risk of developing dementia later in life.
Condition: COVID-19 Pandemic Intervention: Device: 3D Printed Mask Adapter Designed from Facial 3D scans for Fit testing. Sponsor: Barts & The London NHS Trust Not yet recruiting
Conditions: Biodiversity; Food Intake; Nutritional Status Intervention: Behavioral: Promotion of a biodiverse diet Sponsors: University Ghent; HealthBridge Completed
Condition: Irritable Bowel Syndrome Intervention: Behavioral: Low FODMAP diet Sponsor: Taipei Veterans General Hospital, Taiwan Not yet recruiting
In conclusion, it remains unclear if brain-specific regional and temporal changes occur in the expression of the different APP variants during AD progression. Since APP is also found in blood cells, assessing the changes in APP mRNA expression in peripheral blood cells from AD patients has been considering an alternative. However, again the quantification of APP mRNA in peripheral blood cells has generated controversial results. Brain APP protein has been analyzed in only a few studies, probably as it is difficult to interpret the complex pattern of APP variants and fragments. We previously characterized the soluabl...