Plasma dosage of ghrelin, IGF-1, GLP-  1 and leptin related to gastric emptying and esophageal pH-impedance in children with obesity

ConclusionAlthough we found an association between auxological parameters and both leptin and ghrelin levels, this association did not imply an effect on the upper GI motility. Therefore, our hypothesis that alterations of these hormones in children with obesity could affect gastric emptying, triggering GERD, was not supported by our data.
Source: Journal of Endocrinological Investigation - Category: Endocrinology Source Type: research