Evaluation Challenges in the Validation of B7-H3 as Oral Tongue Cancer Prognosticator

In conclusion, B7-H3 was a negative prognosticator for OTSCC patient survival in the subgroup of immune hot tumors, and was not validated as a prognosticator in the full cohort. Our findings suggest that the immune activity of the tumor should be considered when testing immune checkpoints as biomarkers.
Source: Head and Neck Pathology - Category: Pathology Source Type: research