Cancers, Vol. 12, Pages 2707: Glioblastoma Tissue Slice Tandem-Cultures for Quantitative Evaluation of Inhibitory Effects on Invasion and Growth

In conclusion, we describe a straightforward ex vivo system mimicking the in vivo situation of the tumor mass and the normal brain in GBM patients. It reduces animal studies and allows for the direct and reproducible application of test drugs and the precise quantitation of their effects on the bulk tumor mass and on the tumor’s invasive properties.

Source: Cancers - September 20, 2020 Category: Cancer & Oncology Authors: Vasile Sidorcenco Luisa Krahnen Marion Schulz Janina Remy Donat K ögel Achim Temme Ute Kr ügel Heike Franke Achim Aigner Tags: Article Source Type: research