Neuroprotective Effects of SOX5 against Ischemic Stroke by Regulating VEGF/PI3K/AKT pathway.

In conclusion, SOX5 transcription regulates the expression of VEGF to activate the PI3K/AKT pathway, which repaired nerve damage caused by ischemic stroke. Therefore, SOX5 could be a new targetto regulate VEGF which can repair nerve injury induced by ischemic stroke. PMID: 32949698 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32949698?dopt=Abstract

Source: Gene - September 15, 2020 Category: Genetics & Stem Cells Authors: Zhang W, Wu Y, Chen H, Yu D, Zhao J, Chen J Tags: Gene Source Type: research