Immune-related Adverse Events Induced by ICIs in Advanced NSCLC: 
A Meta-analysis and Systematic Review

Conclusion ICIs have different toxicity profile compared with chemotherapy, and their immune-related toxicity is stronger than that of traditional chemotherapy. ICIs induced ir-AEs is organ-specific, and different ICI has specific immune-related toxicity profiles. As ICIs represent a new and distinct class of treatment for NSCLC, this article has systematically illustrated the efficacy and ir-AEs induced by ICIs, hopefully it can be useful for clinicians and patients to get a further understanding of ICIs, and facilitate early prediction, comprehensive diagnosis, and prompt management of ir-AEs by providing status reference and management suggestions, so that ICI can bring more benefit for advanced NSCLC patients. DOI: 10.3779/j.issn.1009-3419.2020.104.07
Source: Chinese Journal of Lung Cancer - Category: Cancer & Oncology Source Type: research