Characterization of stromal tumor-infiltrating lymphocytes and genomic alterations in metastatic lobular breast cancer.

CONCLUSIONS: ILC metastases harbor genomic alterations that may potentially explain endocrine resistance in a large proportion of patients, and present genomic differences as compared to IDC metastases.
PMID: 32943456 [PubMed - as supplied by publisher]

Source: Clinical Cancer Research - September 16, 2020 Category: Cancer & Oncology Authors: Richard F, Majjaj S, Venet D, Rothé F, Pingitore J, Boeckx B, Marchiò C, Clatot F, Bertucci F, Mariani O, Galant C, Van den Eynden GG, Salgado R, Biganzoli E, Lambrechts D, Vincent-Salomon A, Pruneri G, Larsimont DP, Sotiriou C, Desmedt C Tags: Clin Cancer Res Source Type: research