Evaluation of EverLift in the Performance of Polypectomy for Polyps 4-9mm

Conditions:   Colo-rectal Cancer;   Polyp of Colon;   Adenomatous Polyp of Colon Interventions:   Device: Use of EverLift;   Device: Without use of EverLift Sponsor:   Stanford University Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials

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In this study, we examined whether HASPIN inhibitor CHR-6494 suppresses cancer progression in ApcMin/+ mice, a familial colon tumor disease model. Mice were treated by intraperitoneal injection of CHR-6494 for 50 days. Following the treatment period, intestinal polyps were counted and testosterone and spermatogenesis levels were observed. Intraperitoneal administration of CHR-6494 significantly inhibited intestinal polyp development and recovered body weight in ApcMin/+ mice. Although spermatogenesis was inhibited with increasing age in ApcMin/+ mice, CHR-6494 significantly improved blood testosterone levels and spermatoge...
Source: European Journal of Cancer Prevention - Category: Cancer & Oncology Tags: Gastrointestinal cancer Source Type: research
Colonoscopy is the most commonly performed endoscopic examination worldwide and is considered the gold standard for colorectal cancer screening.The quality of examination and endoscopic treatment is affected by a number of factors that are verified by recognized parameters, such as cecal intubation rate and time, withdrawal time, adenoma detection rate and polyp detection rate.The aim of the study was to assess the suitability of 330-degree panoramic colonoscopy for the detection of colorectal lesions and to analyze the functionality of a special endoscope series in regard to cecal intubation rate, cecal intubation time, and withdrawal time.
Source: Journal of the American College of Surgeons - Category: Surgery Authors: Tags: Colon and rectal surgery Source Type: research
Conclusions: Adenomatous polyps are very important in childhood because of rarity. In particular, the presence of cafe au lait spots and a history of malignancy detected in relatives at an early age must be considered for CMMRD.
Source: Journal of Pediatric Hematology Oncology - Category: Hematology Tags: Online Articles: Clinical and Laboratory Observations Source Type: research
AbstractPurposeIGF-1Ec is an isoform of Insulin-like growth factor 1 (IGF-1) and has recently been identified to be overexpressed in cancers including prostate and neuroendocrine tumours. The aim of this paper is to investigate the expression of IGF-1Ec in colorectal cancer and polyps compared to normal colon tissues and its association with recurrent disease using semi-quantitative immunohistochemistry.MethodsImmunohistochemistry for IGF-1Ec expression was performed for colorectal cancer, colorectal polyps and normal colonic tissues. The quantification of IGF-1Ec expression was performed with the use of Image J software a...
Source: Journal of Cancer Research and Clinical Oncology - Category: Cancer & Oncology Source Type: research
A 64-year-old man presented with large colon polyp detected by screening colonoscopy. The colonoscopy showed a 20-mm pedunculated polyp with a thick and bulging stalk in the sigmoid colon (Figure A). Endoscopic ultrasonography revealed that the stalk consisted of a low echoic structure in the submucosa, considering of a cystic component (Figure B, arrows). Although the polyp was suspected of an invasive cancer, biopsies from the polyp head revealed tubular adenoma. Endoscopic resection was performed for pathological diagnosis and local treatment at the patient ’s request.
Source: Clinical Gastroenterology and Hepatology - Category: Gastroenterology Authors: Tags: Electronic Image of the Month Source Type: research
Conclusion Incomplete polyp resection was frequent after polypectomy in routine clinical practice. Serrated histology and proximal location were independent risk factors for incomplete resection. The performance of board-certified gastroenterologists was not superior to that of trainees. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: Endoscopy - Category: Gastroenterology Authors: Tags: Original article Source Type: research
(Ohio State University) Researchers have found a way to send tiny, soft robots into humans, potentially opening the door for less invasive surgeries and ways to deliver treatments for conditions ranging from colon polyps to stomach cancer to aortic artery blockages.
Source: EurekAlert! - Biology - Category: Biology Source Type: news
Colon cancer is the third most common cause of cancer death in the United States. Because people with advanced polyps have triple the risk of developing cancer, it's generally recommended that they have a colonoscopy every three years.
Source: WebMD Health - Category: Consumer Health News Source Type: news
In this study, we aimed at investigating the relationship between diverticula and in vivo colonic features such as total colon length (TCL), using CTC. We also evaluated polyps, neoplastic lesions and the correlation among them. METHODS: This retrospective study considered a series of patients who underwent CTC in our Hospital from 2010 to 2018. We evaluated TCL, the length of each colon segments and sigmoid colon diameter using dedicated software. We verified the presence of diverticula, polyps and neoplasm and measured the number of diverticula using a five-point class scale, evaluating the colonic segments involved...
Source: The British Journal of Radiology - Category: Radiology Authors: Tags: Br J Radiol Source Type: research
Conditions:   Colo-rectal Cancer;   Polyp of Colon;   Adenomatous Polyp of Colon Interventions:   Device: Use of EverLift;   Device: Without use of EverLift Sponsor:   Stanford University Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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