Activation of the innate immune system in children with irritable bowel syndrome evidenced by increased fecal human β-defensin-2

The role of the innate immune system in functional gastrointestinal pain disorders is unclear. We investigated the role of β-defensin-2 and gut permeability in childhood irritable bowel syndrome (IBS) and functional abdominal pain (FAP) symptom generation.

Source: Clinical Gastroenterology and Hepatology - September 18, 2020 Category: Gastroenterology Authors: Robert J. Shulman, Sridevi Devaraj, Margaret Heitkemper Source Type: research