Meta-analysis of Aspirin Monotherapy versus Dual Antiplatelet Therapy after Transcatheter Aortic Valve Implantation

Transcatheter Aortic Valve Implantation (TAVI) is increasingly being performed in patients with severe aortic stenosis1. The current American guidelines recommend dual antiplatelet therapy (DAPT) for the first 3 to 6 months after TAVI in patients who are not on anticoagulation1. These recommendations have been established based on experts ’ opinions due to the lack of clinical trials investigating the optimal antithrombotic therapy in this population. More recently, multiple studies have questioned the benefit of DAPT in reducing thromboembolic outcomes and revealed high bleeding events in patients who received DAPT after TAVI comp ared to aspirin monotherapy2-5.
Source: The American Journal of Cardiology - Category: Cardiology Authors: Source Type: research