Macromolecular biomarkers of chronic obstructive pulmonary disease in exhaled breath condensate.

Macromolecular biomarkers of chronic obstructive pulmonary disease in exhaled breath condensate. Biomark Med. 2020 Jul;14(11):1047-1063 Authors: Kazeminasab S, Emamalizadeh B, Jouyban A, Shoja MM, Khoubnasabjafari M Abstract Biomarkers provide important diagnostic and prognostic information on heterogeneous diseases such as chronic obstructive pulmonary disease (COPD). However, finding a suitable specimen for clinical analysis of biomarkers for COPD is challenging. Exhaled breath condensate (EBC) sampling is noninvasive, rapid, cost-effective and easily repeatable. EBC sampling has also provided recent progress in the identification of biological macromolecules, such as lipids, proteins and DNA in EBC samples, which has increased its utility for clinical scientists. In this article, we review applications involving EBC sampling for the analysis of COPD biomarkers and discuss its future potential. PMID: 32940079 [PubMed - in process]
Source: Future Medicine: Biomarkers in Medicine - Category: Internal Medicine Tags: Biomark Med Source Type: research