The prolongation effect of ilaprazole-based standard triple therapy for Helicobacter pylori

Conclusion: Ten-day STT was more effective than 7-day STT for HP eradication. The eradication rate was not affected by the CYP2C19 genotype.
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Trial/Experimental Study Source Type: research

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Medicina (Kaunas). 2021 Jul 20;57(7):733. doi: 10.3390/medicina57070733.ABSTRACTHelicobacter pylori (HP) is a Gram-negative bacterium which finds its suitable habitat in the stomach. The infection affects about half of the global population with high variability in prevalence among regions and for age. HP is the main causative agent of chronic active gastritis, peptic and duodenal ulcers, and may be the primary cause of gastric cancer or MALT lymphoma. Due to the high rate of failure of eradication therapy in various countries and the increase in antibiotic resistance reported in the literature, there is an ever wider need...
Source: Medicina (Kaunas) - Category: Universities & Medical Training Authors: Source Type: research
Int J Microbiol. 2021 Jun 29;2021:5540560. doi: 10.1155/2021/5540560. eCollection 2021.ABSTRACTHelicobacter pylori (H. pylori) plays a crucial role in the pathogenesis of gastritis, peptic ulcer, and gastric cancer. The presence of pathogenicity islands (PAI) genes contributes to the pathogenesis of many gastrointestinal disorders. Cytotoxin-associated gene A (cagA) and vacuolating cytotoxin gene (vacA) are the most known virulence genes in H. pylori. So, our aim was to study H. pylori virulence genes' role in gastric disorders pathogenesis. Our study included 150 adult patients who suffered dyspeptic symptoms and were ref...
Source: International Journal of Microbiology - Category: Microbiology Authors: Source Type: research
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