Evaluation of the pharmacokinetic drug-drug interaction potential of iohexol, a renal filtration marker

ConclusionsIohexol is unlikely to affect the clinical pharmacokinetics of carboplatin, paclitaxel, gemcitabine, or other agents used in combination with carboplatin treatment. Measuring GFR with iohexol to better dose carboplatin is unlikely to alter the safety or efficacy of chemotherapy through pharmacokinetic drug-drug interactions.
Source: Cancer Chemotherapy and Pharmacology - Category: Cancer & Oncology Source Type: research