Rapid Screening and Quantitation of PAHs in Water and Complex Sample Matrices by Solid ‐Phase Microextraction Coupled to Capillary Atmospheric Pressure Photoionization‐Mass Spectrometry

AbstractA capillary atmospheric pressure photoionization (cAPPI) source was used to analyze polycyclic aromatic hydrocarbons (PAHs) in complex matrices like grilled meat extract and urban dust reference material, as well as screening for PAHs in aqueous samples such as tap and lake water. A high ‐throughput workflow was developed that allowed rapid screening of unknown samples by direct solid‐phase microextraction (SPME) coupled with cAPPI‐MS, with confirmatory gas chromatography performed only for samples containing trace amounts of PAHs. Extraction times were as low as 15 seconds, w ith a total analysis time of 2 minutes per sample for screening. Limits of detections were in the low pg/mL range and in the sub‐pg/mL range for the direct and chromatographic approach, respectively, with a linear dynamic range between 2 and 3 orders of magnitude, as determined for 15 model PAHs. This rapid approach represents an attractive way to screen samples containing non‐polar compounds using an ambient ionization source.

Source: Journal of Mass Spectrometry - September 16, 2020 Category: Chemistry Authors: Mario F. Mirabelli, Renato Zenobi Tags: SPECIAL ISSUE ‐ RESEARCH ARTICLE Source Type: research