Novel BAG3 Variants in African American Patients with Cardiomyopathy: Reduced β-Adrenergic Responsiveness in Excitation-Contraction

We reported 3 novel non-synonymous single-nucleotide variants of Bcl2-associated athanogene 3 (BAG3) in African Americans with heart failure (HF) which are associated with 2-fold increase in cardiac events (HF hospitalization, heart transplant or death).
Source: Journal of Cardiac Failure - Category: Cardiology Authors: Source Type: research