MicroRNA-3614 regulates inflammatory response via targeting TRAF6-mediated MAPKs and NF- κB signaling in the epicardial adipose tissue with coronary artery disease

The inflammatory status of epicardial adipose tissue (EAT) is one of the factors leading to the development of related diseases such as coronary artery disease (CAD). The thickness of CAD EAT increases and is accompanied with increased macrophage infiltration and heightened inflammatory responses. However, microRNAs (miRNAs) regulating the inflammatory responses of macrophages in CAD EAT remain unclear.

Source: International Journal of Cardiology - September 16, 2020 Category: Cardiology Authors: Wenhua Huang, Xinggang Wu, Yajun Xue, Yijun Zhou, Hui Xiang, Wenkai Yang, Yutao Wei Source Type: research