RhTSG-6 inhibits IL-1 β-induced extracellular matrix degradation and apoptosis by suppressing the p38, and JNK pathways in nucleus pulposus cells.

CONCLUSIONS: RhTSG-6 can attenuate ECM degradation and apoptosis in IL-1β-induced NP cells by inhibiting the p38, JNK and ERK pathways, which may contribute to its potential application in the therapy of IDD. PMID: 32936927 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32936927?dopt=Abstract

Source: Folia Histochemica et Cytobiologica - September 18, 2020 Category: Cytology Tags: Folia Histochem Cytobiol Source Type: research