Recording EMT Activity by Lineage Tracing during Metastasis.

Recording EMT Activity by Lineage Tracing during Metastasis.
Dev Cell. 2020 Sep 14;54(5):567-569
Authors: Vieugué P, Blanpain C
Abstract
In this issue of Developmental Cell, Li et al. develop a novel lineage tracing system to record EMT activity during lung metastasis of mammary tumors. Using EMT-tracer mouse models, they reveal that N-cadherin is transiently expressed by most metastasis-initiating cells and demonstrate its functional importance during the metastatic cascade.
PMID: 32931747 [PubMed - in process]

Source: Developmental Cell - September 13, 2020 Category: Cytology Authors: Vieugué P, Blanpain C Tags: Dev Cell Source Type: research