Gut Microbes ’ Impact on Oncogenic Drivers: Location Matters

Recent work by Kadosh et  al. (2020) suggests that mutant p53 activity in gut epithelia is influenced by local production of microbial metabolites. The switch of p53 from tumor suppressor to oncogene is location-dependent and is impacted by microbially derived gallic acid.

Source: Molecular Cell - September 16, 2020 Category: Cytology Authors: Michael G. White, Jennifer A. Wargo Tags: Spotlight Source Type: research