Recommendations for acylcarnitine profile analysis.

Recommendations for acylcarnitine profile analysis.
Ann Biol Clin (Paris). 2020 Sep 15;:
Authors: Nowoczyn M, Acquaviva-Bourdain C, Corne C, Minet-Quinard R, Van Noolen L, Garnotel R, Dessein AF
Abstract
Biochemical diagnosis of hereditary metabolic diseases requires the detection and simultaneous identification of a large number of compounds, hence the interest in metabolic profiles. Acylcarnitine profile allows the identification and quantification of more than thirty compounds. As part of the accreditation process for medical biology examinations according to standard NF EN ISO 15189, the group from SFEIM recommends an approach to accredit acylcarnitine profile. Validation parameters and recommendations are discussed in this specific framework.
PMID: 32933890 [PubMed - as supplied by publisher]

Source: Annales de Biologie Clinique - September 14, 2020 Category: Biochemistry Authors: Nowoczyn M, Acquaviva-Bourdain C, Corne C, Minet-Quinard R, Van Noolen L, Garnotel R, Dessein AF Tags: Ann Biol Clin (Paris) Source Type: research