Sperm retrieval and intracytoplasmic sperm injection outcomes in men with cystic fibrosis disease versus congenital bilateral absence of the vas deferens.

In conclusion, those with CF demonstrated lower sperm quality, greater difficulty with sperm retrieval, and worse ICSI outcomes compared with CBAVD-only patients. Homozygous delta F508 CFTR mutations appear to significantly impair spermatogenesis and sperm function. PMID: 32930103 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32930103?dopt=Abstract

Source: Asian Journal of Andrology - September 10, 2020 Category: Urology & Nephrology Authors: McBride JA, Kohn TP, Mazur DJ, Lipshultz LI, Coward RM Tags: Asian J Androl Source Type: research