China extends tariff exclusion for Varian for a year

Radiation therapy vendor Varian Medical Systems will remain exempt from paying...Read more on AuntMinnie.comRelated Reading: Varian releases update to proton therapy software Varian names Toth as president and COO Siemens raises $3.2B to fund Varian acquisition Why Siemens-Varian deal is a win-win for both companies Siemens to buy Varian in $16B deal
Source: Headlines - Category: Radiology Source Type: news

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AbstractCardiac disease following radiation therapy represents a major consideration in the treatment of a variety of malignancies. Damage to the heart can manifest in a variety of pathologies including ischemic cardiac disease, cardiomyopathy, valvular dysfunction, arrhythmias, and pericarditis. This damage has been shown to directly relate to cardiac radiation dose and to stem from a range of cellular pathways that are often related to fibrosis. The importance of minimizing radiation dose to the heart is especially critical in the pediatric population and when treating disease sites adjacent to the heart. Proton therapy ...
Source: Journal of Thrombosis and Thrombolysis - Category: Hematology Source Type: research
Abstract Proton minibeam radiation therapy (pMBRT) is a new approach in proton radiotherapy, by which a significant increase in the therapeutic index has already been demonstrated in RG2 glioma-bearing rats. In the current study we investigated the response of other types of glioma (F98) and performed a comparative evaluation of tumor control effectiveness by pMBRT (with different levels of dose heterogeneity) versus conventional protons. The results of our study showed an equivalent increase in the lifespan for all evaluated groups (conventional proton irradiation and pMBRT) and no significant differences in the ...
Source: Radiation Research - Category: Physics Authors: Tags: Radiat Res Source Type: research
Breast radiotherapy is associated with an increased risk of ischemic heart disease, particularly for left-sided irradiation due to direct anatomical proximity between the left anterior descending coronary artery (LADCA) and the target volumes [1 –4]. First generation radiotherapy techniques, which relied on wide treatment fields, were associated with a substantial cardiac mortality increase. Fortunately, breast irradiation has benefited from recent technological progresses allowing significant cardiac sparing, such as intensity-modulated radiation therapy (IMRT) [5], proton therapy [6] or deep-inspiration breath hold (DIBH)[7].
Source: Radiotherapy and Oncology - Category: Radiology Authors: Tags: Original Article Source Type: research
First, and perhaps most importantly, Dinh et  al are to be applauded for presenting their prospective series of men treated with proton therapy at the University of Washington and their carefully reported rectal toxicity outcomes in the context of dose-volume histogram analysis as well as differing rectal immobilization devices.1 These result s provide strong evidence suggesting that without the use of a rectal spacer, there is increased rectal toxicity with proton therapy compared with intensity modulated radiation therapy (IMRT).
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Tags: Clinical Investigation Source Type: research
The University of Arkansas Board of Trustees on Friday approved joint ventures between the University of Arkansas for Medical Sciences, Baptist Health and Arkansas Children’s to expand access to radiation therapy as well as to establish the state’s first proton therapy center.
Source: Arkansas Business - Health Care - Category: American Health Source Type: news
To investigate if radiographic imaging changes defined as necrosis correlate with regions in the brain with elevated linear energy transfer (LET) for proton radiation therapy treatments with partial brain involvement in central nervous system (CNS) and head and neck (H&N) cancer patients.
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Source Type: research
Significant advancements in accelerator technology and growing experience with the use of ion beams for medical applications has supported the recent emergence of charged particle therapy facilities worldwide [1]. The benefit over conventional X-ray radiation therapy stems from the advantage of delivering a beam with a finite range. Protons undergo interactions due to their mass and charge, continually slowing down before they come to a complete stop, resulting in a culmination of energy deposition: the ‘Bragg Peak’.
Source: Physica Medica: European Journal of Medical Physics - Category: General Medicine Authors: Tags: Original paper Source Type: research
Abstract Prescription and delivery of protons are somewhat different compared to photons and may influence outcomes (tumour control and toxicity). These differences should be taken into account to fully exploit the clinical potential of proton therapy. Innovations in proton therapy treatment are also required to widen the therapeutic window and determine appropriate populations of patients that would benefit from new treatments. Therefore, strategies are now being developed to reduce side effects to critical normal tissues using alternative treatment configurations and new spatial or temporal-driven optimisation a...
Source: Cancer Radiotherapie - Category: Cancer & Oncology Authors: Tags: Cancer Radiother Source Type: research
Cone beam computed tomography (CBCT) is a volumetric imaging modality currently used for verification of patient positioning in image guided radiation therapy (IGRT), and for assessing the potential need for adaptive radiotherapy (ART) [1,2]. In the patient treatment chain, kV systems mounted on linear accelerators (linacs) acquire images of the patient in the treatment position to verify the patient setup and hence enable adequate irradiation of the target. Geometrical variations of target volumes, organs at risk (OARs), weight changes (loss/gain), tumour regression and/or progression, which may occur during the overall t...
Source: Physica Medica: European Journal of Medical Physics - Category: General Medicine Authors: Tags: Review paper Source Type: research
Conclusion: Comparative preplanning could be beneficial considering multiple therapies for ruling out the best treatment outcomes that could be expected.
Source: Journal of Cancer Research and Therapeutics - Category: Cancer & Oncology Authors: Source Type: research
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