13C/12C breath test ratio after the ingestion of a meal naturally enriched with (13C)carbohydrates is a surrogate marker of insulin resistance and insulin sensitivity in children and adolescents with Type 1 Diabetes

Type 1 diabetes mellitus (T1D) is the result of the loss of β-cell mass due to complex autoimmune processes with consequent insulin deficiency; moreover, clinical and experimental evidence suggests that higher insulin resistance (IR) and impaired insulin sensitivity (IS), can be present in T1D patients [1].

Source: Diabetes Research and Clinical Practice - September 15, 2020 Category: Endocrinology Authors: Marco Marigliano, Yves Schutz, Claudia Piona, Francesca Tomasselli, Mara Tommasi, Massimiliano Corradi, Francesca Olivieri, Elena Fornari, Anita Morandi, Claudio Maffeis Source Type: research