Dark Sweet Cherry (Prunus avium) Phenolics Enriched in Anthocyanins Induced Apoptosis in MDA-MB-453 Breast Cancer Cells through MAPK-Dependent Signaling and Reduced Invasion via Akt and PLC γ-1 Downregulation.

In conclusion, DSC phenolics inhibited MDA-MB-453 breast cancer cells by targeting cell signaling pathways that induce apoptosis and suppress cell invasion, with ACN showing enhanced chemopreventive activities. PMID: 32924599 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32924599?dopt=Abstract

Source: Nutrition and Cancer - September 13, 2020 Category: Cancer & Oncology Authors: Layosa MAA, Lage NN, Chew BP, Atienza L, Mertens-Talcott S, Talcott S, Noratto GD Tags: Nutr Cancer Source Type: research