A Single Prophylactic Dose of Ondansetron Given at Cessation of Postoperative Propofol Sedation Decreases Postoperative Nausea and Vomiting in Cardiac Surgery Patients: A Randomized Controlled Trial.

CONCLUSIONS: These findings support the routine administration of ondansetron prophylaxis at the time of discontinuation of postoperative propofol sedation before extubation in patients following cardiac surgery. Further research is warranted to optimize PONV prophylaxis in cardiac surgery patients. PMID: 32925337 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/32925337?dopt=Abstract

Source: Anesthesia and Analgesia - September 16, 2020 Category: Anesthesiology Authors: Wang EHZ, Sunderland S, Edwards NY, Chima NS, Yarnold CH, Schwarz SKW, Coley MA Tags: Anesth Analg Source Type: research