[Editors' Choice] Metabolic control of NLRP3 inflammasome by itaconation

The Krebs cycle–derived immunometabolite itaconate constrains NLRP3 inflammasome activation and IL-1β release.

Source: Science Translational Medicine - September 15, 2020 Category: Biomedical Science Authors: Van den Bossche, J. Tags: Editors ' Choice Source Type: research