Screening Algorithms to Reduce Burden of Pediatric HIV Testing: A Systematic Review and Meta-analysis

Conclusions: Few studies have evaluated the use of screening tools for HIV diagnosis in children. Screening tools that exist showed only moderate sensitivity and specificity and missed a substantial number of HIV-infected children in high-prevalence areas. In outpatient settings, the use of a screening tool may help reduce the number of HIV tests needed to identify an HIV-infected child, but at the cost of missed diagnoses. Further studies are needed to determine whether this represents a resource-saving mechanism.
Source: The Pediatric Infectious Disease Journal - Category: Infectious Diseases Tags: HIV Reports Source Type: research

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CONCLUSIONS: The distribution of sexually acquired HCV was sparsely scattered across countries/cities in the Asia-Pacific region. The threat of overlapping risk differed by locations, whereas transnational outbreaks remained uncommon. The paucity of information has hindered progress with comprehensive assessment in the Asia-Pacific region, where seroprevalence of HCV among HIV-positive MSM was relatively high. PMID: 32969173 [PubMed - in process]
Source: Journal of the International AIDS Society - Category: Infectious Diseases Tags: J Int AIDS Soc Source Type: research
by Justin C. Smith Molldrem and Smith’s thoughtful article “Reassessing the Ethics of Molecular HIV Surveillance in the Era of Cluster Detection and Response: Toward HIV Data Justice,” calls attention to vitally important considerations in the implementation of molecular HIV surveillance (MHS) in HIV cluster detection response (CDR) efforts. The authors are rightly concerned with the myriad ethical questions posed by how these efforts are carried out, and they echo concerns that some members of the HIV advocacy community in the United States have raised.…
Source: blog.bioethics.net - Category: Medical Ethics Authors: Tags: Editorial-AJOB Featured Posts HIV/AIDS Technology Source Type: blogs
In conclusion, common reasons for admission of epidemic KS patients include advanced disease, severe anemia, respiratory tract infections, and signs and symptoms of sepsis. Signs and symptoms of sepsis are independent predictors of mortality in these patients.
Source: Medicine - Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
AbstractPurpose of ReviewHIV pre-exposure prophylaxis (PrEP) is a safe and effective preventive intervention that could play a central role in ending the HIV epidemic. However, low uptake in general, and among certain social groups in particular, underscores the need to identify and address barriers to PrEP use. PrEP stigma has emerged as a key factor interfering with PrEP interest, uptake, and continuation. The purpose of this article is to describe and contextualize PrEP stigma and to offer recommendations on how to address it in future PrEP implementation initiatives.Recent FindingsPrEP users are commonly stereotyped as...
Source: Current HIV/AIDS Reports - Category: Infectious Diseases Source Type: research
CONCLUSION: Information about the impact of epidemics on parents and children is relevant to policy makers to aid them in developing strategies to help families cope with epidemic/pandemic-driven adversity and ensure their children's healthy development. PMID: 32980318 [PubMed - as supplied by publisher]
Source: Jornal de Pediatria - Category: Pediatrics Authors: Tags: J Pediatr (Rio J) Source Type: research
Michael F. CannonNurses have been on the front line of the COVID-19 pandemic as they have been for every public health crisis from the Spanish influenza to the AIDS epidemic. Yet state governments have made it harder for nurses to help victims of this and other diseases.In 2004, California enacted a law that restricts the ability of hospitals to assign nurses to where patients need them, which increases the cost of care. In that year, California became the first state to mandate inpatient facilities adhere to predeterminednurse ‐​to‐​patient ratios. The law restricts the number of patients each nurse can ...
Source: Cato-at-liberty - Category: American Health Authors: Source Type: blogs
By SOMA SEN I keep hearing the voices of colleagues and friends that have been part of the AIDS epidemic compare it to the current COVID-19 pandemic. In fact Dr. Kathy Creticos, Director of Infectious Disease at Howard Brown Health spoke about the politicization of both the pandemics.  “Here we are in 2020 with this disease that kills people, that we don’t have any treatments for, that we really don’t understand the full manifestation and presentation biology of the virus,” Creticos said In the final segment of an interview with Contagion during International AIDS Society (IAS) A...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: Health Policy Public Health AIDS HIV Soma Sen Source Type: blogs
Authors: Khan S, Spiegelman D, Walsh F, Mazibuko S, Pasipamire M, Chai B, Reis R, Mlambo K, Delva W, Khumalo G, Zwane M, Fleming Y, Mafara E, Hettema A, Lejeune C, Chao A, Bärnighausen T, Okello V Abstract INTRODUCTION: The WHO recommends antiretroviral treatment (ART) for all HIV-positive patients regardless of CD4 count or disease stage, referred to as "Early Access to ART for All" (EAAA). The health systems effects of EAAA implementation are unknown. This trial was implemented in a government-managed public health system with the aim to examine the "real world" impact of EAAA on care ret...
Source: Journal of the International AIDS Society - Category: Infectious Diseases Tags: J Int AIDS Soc Source Type: research
Inter-subtype recombinants play an increasingly central role in the complex and dynamic HIV/AIDS epidemic. At present, 106 Circulate recombinant forms (CRFs) have been identified worldwide. In 2000, CRF07_BC and CRF08_BC were first reported in China, and novel CRFs identified in China has soared since 2013. Inter-subtype recombinant viruses, especially CRF01_AE and CRF07_BC, have become the predominant strains of the HIV-1 epidemic in China1. The double infection between CRFs established more optimal conditions for the second-generation recombination2, and many second-generation recombinants were represented by the recombi...
Source: Journal of Infection - Category: Infectious Diseases Authors: Source Type: research
Inter-subtype recombinants play an increasingly central role in the complex and dynamic HIV/AIDS epidemic. At present, 106 Circulate recombinant forms (CRFs) have been identified worldwide. In 2000, CRF07_BC and CRF08_BC were first reported in China, and novel CRFs identified in China has soared since 2013. Inter-subtype recombinant viruses, especially CRF01_AE and CRF07_BC, have become the predominant strains of the HIV-1 epidemic in China.1 The double infection between CRFs established more optimal conditions for the second-generation recombination,2 and many second-generation recombinants were represented by the recombi...
Source: Journal of Infection - Category: Infectious Diseases Authors: Tags: Letter to the Editor Source Type: research
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