Lysine oxidase exposes a dependency on the thioredoxin antioxidant pathway in triple-negative breast cancer cells

ConclusionsLO exposes a redox vulnerability of TNBC cells to TXNRD inhibition by rendering tumor cells dependent on the thioredoxin antioxidant pathway for survival.

http://link.springer.com/10.1007/s10549-020-05801-4

Source: Breast Cancer Research and Treatment - September 16, 2020 Category: Cancer & Oncology Source Type: research