Should It Be Called "Suicide" or "Withdrawal of LVAD Support"?

Left ventricular assist devices (LVADs) have become the standard of care for patients with end-stage heart failure refractory to conventional therapy to improve their survival and quality of life.1 But when LVAD therapy no longer meets their treatment-related preferences, goals, and values, patients may request withdrawal of LVAD support. Especially when patients are not acutely ill and they are medically stable, this request raises ethical concerns among clinicians. Prior research has shown that some clinicians (13%) perceive turning off an LVAD is the same as physician-assisted suicide or euthanasia.
Source: Journal of Pain and Symptom Management - Category: Palliative Care Authors: Tags: Letter Source Type: research

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hat H Abstract PURPOSE: Individuals with poor physical and mental health may face elevated risk for suicide, particularly suicide by firearm. METHODS: This retrospective cohort study used statewide, longitudinally-linked ED patient record and mortality data to examine 12-month incidence of firearm suicide among emergency department (ED) patients presenting with a range of physical health problems. Participants included all residents presenting to a California ED in 2009-2013 with nonfatal visits for somatic diagnoses hypothesized to increase suicide risk, including myocardial infarction, congestive heart fail...
Source: Annals of Epidemiology - Category: Epidemiology Authors: Tags: Ann Epidemiol Source Type: research
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Left ventricular assist devices (LVADs) have become the standard of care for patients with end-stage heart failure refractory to conventional therapy, to improve their survival and quality of life.1 But when LVAD therapy no longer meets their treatment-related preferences, goals and values, patients may request withdrawal of LVAD support. Especially when patients are not acutely ill and they are medically stable, this request raises ethical concerns among clinicians. Prior research has shown some clinicians (13%) perceive turning off an LVAD is the same as physician assisted suicide or euthanasia.
Source: Journal of Pain and Symptom Management - Category: Palliative Care Authors: Source Type: research
Who remembers Jack Kevorkian, Doctor Death? He was found guilty in 1998 of second-degree murder. Still, it was because of his advocacy that the terminally ill patient’s right to die by physician-assisted suicide was propelled into the public arena. And who can forget Brittany Maynard? It was her advocacy for physician-assisted suicide that reignited the […]Find jobs at  Careers by KevinMD.com.  Search thousands of physician, PA, NP, and CRNA jobs now.  Learn more.
Source: Kevin, M.D. - Medical Weblog - Category: General Medicine Authors: Tags: Conditions heart failure Pain Management Palliative Care Source Type: blogs
ConclusionsA history of MST is common among older women veterans and associated with a range of medical and mental health diagnoses. These findings call attention to the need for additional research in this understudied population, and the importance of trauma-informed care approaches for women across the lifespan.
Source: Journal of General Internal Medicine - Category: Internal Medicine Source Type: research
This study sought to investigate what could be learned from how these men have fared. The men were born in 1925-1928 and similar health-related data from questionnaires, physical examination, and blood samples are available for all surveys. Survival curves over various variable strata were applied to evaluate the impact of individual risk factors and combinations of risk factors on all-cause deaths. At the end of 2018, 118 (16.0%) of the men had reached 90 years of age. Smoking in 1974 was the strongest single risk factor associated with survival, with observed percentages of men reaching 90 years being 26.3, 25.7, ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
In conclusion, we identified a novel Bcl-2 inhibitor by QSAR screening, which exerted significant cytotoxic activity in breast cancer cells through inducing mitochondria-mediated apoptosis. Introduction Apoptosis is a process of cellular suicide through which unwanted or unhealthy cells are eliminated during organism development or cellular stress (Reed, 2002; Fernald and Kurokawa, 2013). Deregulated apoptosis is a characteristic of cancers (Doi et al., 2012; Roizen, 2012). The B-cell lymphoma-2 (Bcl-2) family is composed of pro- and anti-apoptotic proteins, plays pivotal role in the mitochondrial pathway of apoptosi...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
 In his teens, Tony Hoffman was a BMX Amateur being featured on magazine covers. But soon after, he was a drug addict living in the streets and ultimately ending in prison. After his parole, a now clean Tony returned to the BMX world in a big way: by taking the silver medal in the 2016 Olympics. Since then, Tony has dedicated his life to helping others with addiction issues with his motivational speaking and special projects. Subscribe to Our Show! And Remember to Review Us! About Our Guest After paroling prison on December 13, 2008, Tony Hoffman started living out his dream, with his addiction behind...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: General Recovery Sports The Psych Central Show Addiction BMX Gabe Howard Olympics prison Tony Hoffman Vincent M. Wales Source Type: blogs
 In his teens, Tony Hoffman was a BMX Amateur being featured on magazine covers. But soon after, he was a drug addict living in the streets and ultimately ending in prison. After his parole, a now clean Tony returned to the BMX world in a big way: by taking the silver medal in the 2016 UCI BMX World Championships. Since then, Tony has dedicated his life to helping others with addiction issues with his motivational speaking and special projects. Subscribe to Our Show! And Remember to Review Us! About Our Guest After paroling prison on December 13, 2008, Tony Hoffman started living out his dream, with h...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: General Recovery Sports The Psych Central Show Addiction BMX Gabe Howard Olympics prison Tony Hoffman Vincent M. Wales Source Type: blogs
In conclusion, long-term aerobic exercise appears to attenuate the decline in endothelial vascular function, a benefit which is maintained during chronological aging. However, currently there is not enough evidence to suggest that exercise interventions improve vascular function in previously sedentary healthy older adults. Hijacking the Proteasome to Dispose of Unwanted Molecules in Age-Related Disease https://www.fightaging.org/archives/2019/03/hijacking-the-proteasome-to-dispose-of-unwanted-molecules-in-age-related-disease/ Cells are equipped with a protein disposal system in the form of the proteaso...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
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