Structures of Arabidopsis thaliana oxygen-sensing plant cysteine oxidases 4 and 5 enable targeted manipulation of their activity [Plant Biology]

In higher plants, molecular responses to exogenous hypoxia are driven by group VII ethylene response factors (ERF-VIIs). These transcriptional regulators accumulate in the nucleus under hypoxia to activate anaerobic genes but are destabilized in normoxic conditions through the action of oxygen-sensing plant cysteine oxidases (PCOs). The PCOs catalyze the reaction...

Source: Proceedings of the National Academy of Sciences - September 14, 2020 Category: Science Authors: Mark D. White, Laura Dalle Carbonare, Mikel Lavilla Puerta, Sergio Iacopino, Martin Edwards, Kate Dunne, Elisabete Pires, Colin Levy, Michael A. McDonough, Francesco Licausi, Emily Flashman Tags: Biological Sciences Source Type: research