Fusogen-mediated neuron-neuron fusion disrupts neural circuit connectivity and alters animal behavior [Neuroscience]

The 100-y-old neuron doctrine from Ramón y Cajal states that neurons are individual cells, rejecting the process of cell−cell fusion in the normal development and function of the nervous system. However, fusogens—specialized molecules essential and sufficient for the fusion of cells—are expressed in the nervous system of different species under...

Source: Proceedings of the National Academy of Sciences - September 14, 2020 Category: Science Authors: Rosina Giordano-Santini, Eva Kaulich, Kate M. Galbraith, Fiona K. Ritchie, Wei Wang, Zhaoyu Li, Massimo A. Hilliard Tags: Biological Sciences Source Type: research