How the mitochondrial calcium uniporter complex (MCUcx) works [Physiology]

The MCU holocomplex, MCUcx Cytosolic calcium enters the mitochondrial matrix through the mitochondrial calcium uniporter (MCU) where it acts as a signal that regulates ATP production (1), metabolic fuel selection (1–3), and if excessively high, triggers cell death (4). The complete complex of the MCU subunits is now referred to...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Tags: Commentaries Source Type: research