Reply to Liu: The disassembly of the actin cytoskeleton is an early event during NETosis [Biological Sciences]

We used quantitative, high-resolution live-cell imaging of neutrophil-like human cells (dHL60) and mouse and human blood-derived polymorphonuclear neutrophils (PMNs) stimulated with ionomycin, lipopolysaccharide (LPS), or Candida albicans to identify 13 cellular events occurring during neutrophil extracellular trap formation (NETosis) (1). Following thousands of single cells over time showed that these...

Source: Proceedings of the National Academy of Sciences - September 14, 2020 Category: Science Authors: Hawa Racine Thiam, Siu Ling Wong, Rong Qiu, Mark Kittisopikul, Amir Vahabikashi, Anne E. Goldman, Robert D. Goldman, Denisa D. Wagner, Clare M. Waterman Tags: Letters Source Type: research