Functional actin cytoskeleton is required in early stage of NETosis induction [Biological Sciences]

Neutrophil extracellular trap formation (NETosis) is a dynamic process featuring nuclear chromatin extrusion and extracellular trap formation (1) in which ruptures of nuclear envelope and plasma membrane are prerequisite events. Thiam et al. (1) analyze several important cellular events, including cytoskeleton organization, during NETosis using time-lapse microscopy. They conclude that...

Source: Proceedings of the National Academy of Sciences - September 14, 2020 Category: Science Authors: Ming-Lin Liu Tags: Letters Source Type: research