Brain scans may help predict response to OCD therapies

Differences in brain activity seen on scans taken before psychotherapy for obsessive-compulsive disorder corresponded with responses to treatment.
Source: NIH Research Matters from the National Institutes of Health (NIH) - Category: Consumer Health News Source Type: news

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CONCLUSIONS: The study findings demonstrate that associations between brain activation and treatment response were treatment specific to CBT relative to a control psychotherapy and that these associations were stable from adolescence to mature adulthood. Such treatment-specific associations are important for the development of biomarkers to personalize treatment in OCD. PMID: 32854533 [PubMed - as supplied by publisher]
Source: The American Journal of Psychiatry - Category: Psychiatry Authors: Tags: Am J Psychiatry Source Type: research
Mental health flows from the ceramic jug psychotherapist Lori Gottlieb keeps on her desk. There’s nothing special about the jug—a minor accessory in an office designed with the sort of tidy impersonality common to her field. And there’s no special elixir in it—just water. But all the same, the jug provides a certain kind of healing. When patients are struggling, crying, overcome in some way, Gottlieb, a Los Angeles based practitioner and author of the book Maybe You Should Talk to someone, will offer up a cup of water, pour it for them and hand it across. In that small gesture is a whole constellati...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 Source Type: news
CONCLUSIONS: The remission of the patient suggested that CCT could be an alternative intervention for treatment-refractory OCD and those with severe OCD could be cured in short-term. PMID: 31756555 [PubMed - as supplied by publisher]
Source: Asian Journal of Psychiatry - Category: Psychiatry Tags: Asian J Psychiatr Source Type: research
Conclusion: Some patients with psychiatric syndromes and increased ANA titers may suffer from psychiatric variants of SLE, even if the American College of Rheumatology criteria for SLE are not met. Whether the psychiatric symptoms in our patient represent a prodromal stage with the later manifestation of full-blown SLE or a subtype of SLE with isolated CNS involvement remains unclear. Regardless, early diagnosis and initiation of immunosuppressive treatment are essential steps in preventing further disease progression and organ damage. Intrathecal ANAs with extractable nuclear antigen differentiation may be a more sensitiv...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Conclusion It is clear that clinically, there is still much to be learnt about alexithymia and its relationship with a range of related phenomena. Firstly, is alexithymia a continuous and stable trait independent of psychological or somatic symptomology that is developed during childhood? Or is it instead a reactive state induced by trauma and distress at any age, which serves to defend against intense and upsetting emotions? This impacts on treatment options. For example, should we be focussing on early childhood interventions which target the child's emotional environment and parenting to encourage emotional exp...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
This study, therefore, compares reappraisal of negative, positive, neutral, and alcohol-related images at a behavioral and neural level between ADPs and healthy controls (HCs).Thirty-nine ADPs and 39 age-, gender-, and education-matched HCs performed an emotion reappraisal task during functional magnetic resonance imaging (fMRI), and craving was measured before and after the reappraisal task. During the emotion reappraisal task, participants were instructed to either attend or reappraise positive, negative, neutral, or alcohol-related images, and to indicate their experienced emotion on a visual analogue scale (VAS).Both A...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Conclusion We believe our diagnosis of schizo-obsessive disorder in the described patient is appropriate due to his symptoms of schizophrenia and OCD. The OCS at first seemed to have retarded the psychotic manifestation; however, the negative and cognitive symptoms of schizophrenia associated with OCS were prominent, and we believe this greatly contributed to the poor prognosis of our patient. The improvement of his OCS occurred with the emergence of an over-valued idea, corroborating the existence of a schizo-obsessive spectrum modulated by the presence and extent of phenomenological features related to insight. Therefore...
Source: Innovations in Clinical Neuroscience - Category: Neuroscience Authors: Tags: Case Report Current Issue Neurodegenerative Disease Schizophrenia comorbidity insight obsessive compulsive disorder Source Type: research
Washing hands needlessly dozens of times of day. Spending so much time perfecting schoolwork that it never gets turned in.These are typical behaviors for people with obsessive compulsive disorder, or OCD, a lifelong illness marked by repetitive thoughts and actions that can seriously impair work performance, relationships and quality of life. OCD is most commonly treated with medication and a form of psychotherapy called cognitive behavioral therapy. Unfortunately, cognitive behavioral therapy does not help everyone with OCD, and the treatment can be expensive and time-consuming.Now, UCLA researchers have developed a way t...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
UCLA researchers report that people with obsessive-compulsive disorder, when treated with a special form of talk therapy, demonstrate distinct changes in their brains as well as improvement in their symptoms.In the study, published in  Translational Psychiatry, people with OCD underwent daily cognitive behavioral therapy, or CBT, to learn how to better resist compulsive behaviors and to decrease distress. Within one month, they had developed extensive increases in the strength of the connections between regions of their brains — which may reflect the participants gained new non-compulsive behaviors and thought p...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
“I’m such a sinner. I’m supposed to have pure thoughts. I’m so wicked!” Destiny’s incessant thoughts compelled her to pray, sing hymns, confess, and repent to no avail. Her religious leaders kept telling her that she was not a sinner. They reassured her by telling her that she was a good person. She didn’t know her reassurance seeking was actually a compulsion that kept strengthening her OCD. Her anguish and her need to control her thoughts were affecting her overall functioning. Every time she experienced “impure” thoughts she felt unworthy of happiness or anything go...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Brain and Behavior OCD Psychology Psychotherapy Acceptance And Commitment Therapy Compulsions critical thinking Obsessions Obsessive Compulsive Disorder Reassurance Scrupulosity validation seeking Source Type: blogs
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