Some Psoriasis Meds May Also Help Prevent Heart Disease

Chronic inflammation in people with psoriasis is associated with the development of plaque in heart arteries, which increases the risk of coronary artery disease. In biologic therapy, patients receive protein-based infusions to reduce inflammation.
Source: WebMD Health - Category: Consumer Health News Source Type: news

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This study provides characterization of a lipid-rich necrotic core, a dangerous type of coronary plaque made up of dead cells and cell debris that is prone to rupture. Ruptured plaque can lead to a heart attack or stroke. The analysis involved 209 middle-aged patients (ages 37-62) with psoriasis who participated in the Psoriasis Atherosclerosis Cardiometabolic Initiative at the National Institutes of Health, an ongoing observational study. Of these participants, 124 received biologic therapy, and 85 were in the control group, treated only with topical creams and light therapy. To measure the effects of biologic ther...
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
Title: Some Psoriasis Meds May Also Help Prevent Heart DiseaseCategory: Health NewsCreated: 9/15/2020 12:00:00 AMLast Editorial Review: 9/16/2020 12:00:00 AM
Source: MedicineNet Heart General - Category: Cardiology Source Type: news
(American Heart Association) Biologic therapy for psoriasis - protein-based infusions to suppress inflammation - was associated with a significant reduction in high-risk plaque in heart arteries, over one-year, according to new research.The positive association between biologic therapy and a decrease in high-risk plaque in heart arteries was significant after adjusting for cardiovascular risk factors and psoriasis severity.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
Carotid lumen diameter derived from ultrasound scans was linked to a higher...Read more on AuntMinnie.comRelated Reading: Ultrasound shows heart disease risk from psoriasis MRI of carotid artery aids cardiovascular risk assessment Can AI reliably measure carotid intima-media thickness? Can mild carotid atherosclerosis hurt mental cognition? US spots subclinical atherosclerosis in low-risk women
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
In this study, we applied a well studied prediction model developed on data from five CpG sites, to increase the practicability of these tests. We have determined the biological age of the heart, specifically of the right atrium (RA) and left atrium (LA), and of peripheral blood leucocytes, by measuring the mitotic telomere length (TL) and the non-mitotic epigenetic age (DNAmAge). We found that DNAmAge, of both atrial tissues (RA and LA), was younger in respect to the chronological age (-12 years). Furthermore, no significant difference existed between RA and LA, suggesting that, although anatomically diverse and ex...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Authors: Dai D, Wu H, He C, Wang X, Luo Y, Song P Abstract Psoriasis Vulgaris (PV) not only affects patients' skin health but also increases the risk of coronary heart disease and diabetes, which brings both physical and mental harms. Its pathogenesis is complex, and the multi-target effect of traditional Chinese medicine (TCM) is especially advantageous. Because a considerable number of randomized controlled trials related to TCM exhibit design defects, small sample size or inadequate intervention time, so the status of TCM in the treatment of PV cannot be fully clarified. We reviewed the controlled clinical trial...
Source: Journal of Dermatological Treatment - Category: Dermatology Tags: J Dermatolog Treat Source Type: research
Authors: Oszukowska M, Koz┼éowska M, Kaszuba A Abstract Introduction: Psoriasis is considered as a risk factor for atherosclerosis and contributes to myocardial infarction, ischemic heart disease and brain stroke. Aim: To estimate the atherogenic potential of psoriasis by analysing antioxidative and prooxidative factors (paraoxonase-1, α-tocopherol, uric acid, homocysteine), compare levels of these parameters between groups of psoriatic patients and healthy individuals as well as to analyse the impact of psoriasis severity and duration on the factors under the study and to define correlation between the m...
Source: Advances in Dermatology and Allergology - Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research
In conclusion, our study demonstrated that Nrf2 deficiency promoted the increasing trend of autophagy during aging in skeletal muscle. Nrf2 deficiency and increasing age may cause excessive autophagy in skeletal muscle, which can be a potential mechanism for the development of sarcopenia. To What Degree is Chondrocyte Hypertrophy in Osteoarthritis Due to Cellular Senescence? https://www.fightaging.org/archives/2020/04/to-what-degree-is-chondrocyte-hypertrophy-in-osteoarthritis-due-to-cellular-senescence/ Senescent cells are large. They do not replicate, that function is disabled, but it is as if they go ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
(Natural News) Psoralea corylifolia or babchi is a medicinal herb that is popular among traditional Chinese medicine and Ayurveda practitioners. It is used to treat various skin diseases, including rashes, psoriasis, leprosy, and leucoderma – a condition that causes the appearance of white patches due to loss of melanin. However, several studies have reported that P. corylifolia has other clinical applications, and...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
Major studies have shown that the risk of a cardiovascular event is increased in patients with psoriasis. However, most of these studies, often do not have a clearly documented history of cardiovascular disease in the populations studied. In addition, there are no systematic studies and reports correlating the severity of psoriasis with the complexity of CAD, as quantified by SYNTAX score. In 2005, a team of researchers proposed a system of coronary heart disease complexity in order to select optimal reperfusion technique in coronary patients.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Innate Immunity and Inflammation Source Type: research
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