Impact of adjuvant chemotherapy or tamoxifen-alone on the ovarian reserve of young women with breast cancer

ConclusionsBoth AC-based regimens and CMF significantly compromise ovarian reserve, without a recovery beyond 12  months post-chemotherapy. In contrast, tamoxifen-only treatment does not seem to alter ovarian reserve. These data indicate that the commonly used chemotherapy regimens but not the hormonal therapy compromise future reproductive potential.
Source: Breast Cancer Research and Treatment - Category: Cancer & Oncology Source Type: research