Astrocyte elevated gene-1 serves as a target of miR542 to promote glioblastoma proliferation and invasion.

CONCLUSION: The in vitro findings demonstrated that miR542 inhibited the migration and proliferation of U251 cells and suppressed EMT through targeting AEG-1, indicating that miR542 may be a potential anti-cancer target for GBM.
PMID: 32925290 [PubMed - as supplied by publisher]

Source: Chinese Medical Journal - September 7, 2020 Category: General Medicine Authors: Li C, Liu HL, Zhou YM, Shi YC, Zhang ZB, Chen L, Feng SY Tags: Chin Med J (Engl) Source Type: research