Deletion of muscarinic acetylcholine receptor 3 in microglia impacts brain ischemic injury.

In conclusion, our data suggest that the upregulation of m3R in microglia and monocytes in stroke has a beneficial effect on the clinical outcome in male mice.
PMID: 32927021 [PubMed - as supplied by publisher]

Source: Brain, Behavior, and Immunity - September 10, 2020 Category: Neurology Authors: Costa A, Haage V, Yang S, Wegner S, Ersoy B, Ugursu B, Rex A, Kronenberg G, Gertz K, Endres M, Wolf SA, Kettenmann H Tags: Brain Behav Immun Source Type: research