Dose Volume Histogram Constraints in Patients with Head and Neck Cancer treated with Surgery and Adjuvant HDR Brachytherapy: A Proposal of the Head and Neck and Skin GEC ESTRO Working Group

The recent update of the web-based GEC-ESTRO handbook of brachytherapy [1] has brought into attention the lack of standardized constraints based on dose volume histogram (DVH) data in head and neck brachytherapy. This is specially noteworthy in an anatomical area where treatment complications may be severe in a substantial number of cases.
Source: Radiotherapy and Oncology - Category: Radiology Authors: Tags: Original Article Source Type: research

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India has a longstanding tradition in the practice of brachytherapy and has actively contributed to the scientific literature by conducting prospective studies, clinical audits, developing innovative techniques, and performing randomized studies. Indian investigators have also contributed to international collaborative research, education, training programs along with guideline development for brachytherapy in cervix and head and neck cancers. The present article summarizes the key contributions to scientific literature, current infrastructure, skill set for brachytherapy, existing challenges, and strategy to further stren...
Source: Brachytherapy - Category: Cancer & Oncology Authors: Source Type: research
nge R Abstract BACKGROUND: The Head and Neck and Skin (HNS) Working group of the GEC-ESTRO acknowledges the lack of widely accepted Dose Volume Histogram (DVH) constraints in adjuvant head and neck brachytherapy and issues recommendations to minimize mandibular Osteoradionecrosis (ORN) and Soft Tissue Necrosis (STN). METHODS: A total of 227 patients with the diagnosis of head and neck cancer treated with surgery and adjuvant HDR brachytherapy alone or combined with other treatment modalities during the period 2000-2018 were analyzed. RESULTS: STN was observed in 28 out of 227 cases (12.3%) with an averag...
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - Category: Radiology Authors: Tags: Radiother Oncol Source Type: research
We have read with great interest the GEC-ESTRO ACROP recommendations for head and neck cancer brachytherapy [1]. In their article, the authors defined magnetic resonance imaging (MRI) as feasible for treatment planning. MRI is commonly used for diagnosis and staging of many diseases, and for target delineation. Benefit is well-known for brachytherapy and MRI guided brachytherapy (MRgBT), is recommended by gyn-GEC ESTRO for cervical cancer and more particularly in EMBRACE II protocol [2]. Some teams have also developed MRI workflow for prostate brachytherapy [3].
Source: Radiotherapy and Oncology - Category: Radiology Authors: Tags: Letter to the Editor Source Type: research
Due to the world-wide introduction of the stepping HDR source based personalized treatment planning and dose-volume optimization procedure in Head and Neck brachytherapy practice, the GEC-ESTRO Head and Neck Working Group published in 2017 an update [2] of the previously (2009) published treatment recommendations [3].
Source: Radiotherapy and Oncology - Category: Radiology Authors: Tags: Letter to the Editor Source Type: research
Due to the world-wide introduction of the stepping HDR source based personalized treatment planning and dose-volume optimization procedure in Head and Neck brachytherapy practice, the GEC-ESTRO Head and Neck Working Group published in 2017 an update [2] of the previously (2009) published treatment recommendations [3].
Source: Radiotherapy and Oncology - Category: Radiology Authors: Tags: Letter to the Editor Source Type: research
Conclusions: Our palliative treatment technique appears to be safe, effective, and less invasive, and could be a treatment option for symptomatic patients with head and neck cancer. PMID: 32695200 [PubMed]
Source: Journal of Contemporary Brachytherapy - Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
Authors: Dilalla V, Chaput G, Williams T, Sultanem K Abstract The Canadian Cancer Society estimated that 220,400 new cases of cancer would be diagnosed in 2019. Of the affected patients, more than 60% will survive for 5 years or longer after their cancer diagnosis. Furthermore, nearly 40% will receive at least 1 course of radiotherapy (rt). Radiotherapy is used with both curative and palliative intent: to treat early-stage or locally advanced tumours (curative) and for symptom management in advanced disease (palliative). It can be delivered systemically (external-beam rt) or internally (brachytherapy). Although tec...
Source: Current Oncology - Category: Cancer & Oncology Tags: Curr Oncol Source Type: research
AbstractHead and neck cancer treatment includes a multidisciplinary approach involving all specialties. Surgery and radiotherapy are equally effective in controlling small tumors. Intensity-modulated radiotherapy (IMRT) and interstitial brachytherapy (ISBT) play an important role in the treatment of head and neck cancers. Both are proved to be highly conformal techniques of radiotherapy. Our aim is to compare dosimetric aspects of ISBT alone, IMRT alone, and IMRT combined with ISBT in early stage node negative oral cavity cancer. Ten cases of histopathologically proven early stage node negative oral cavity cancer were trea...
Source: Indian Journal of Surgical Oncology - Category: Cancer & Oncology Source Type: research
Surgery remains the primary modality for resectable, non-metastatic disease. Here, we explore the safety and oncologic benefit of cesium 131 brachytherapy combined with salvage surgical resection.
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Tags: Management of Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma Source Type: research
Conclusions: CT-based surface mould brachytherapy results in better conformity of superficial lesions on small, irregular surfaces such as the nose and inner canthus than electrons with a slightly higher skin dose. PMID: 31969913 [PubMed]
Source: Journal of Contemporary Brachytherapy - Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
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