The Rise and Fall of Otosclerosis: A Population-based Study of Disease Incidence Spanning 70 Years

Objective: Although it is commonly held that otosclerosis has become increasingly uncommon over recent decades, no population-based data exist to characterize this trend. Moreover, because most large epidemiologic databases within the United States primarily include cancer data, even the modern incidence of otosclerosis is unknown. The chief objective of the current work was to characterize the trend in the incidence of otosclerosis over 70 years using the unique resources of the Rochester Epidemiology Project. Study Design: Population-based study. Patients: Residents of Olmsted County, Minnesota diagnosed with otosclerosis. Main Outcome Measure: Disease incidence from 1950 to 2017. Results: From 1950 to 2017, 614 incident cases of otosclerosis were identified. The incidence rose from 8.9 per 100,000 person-years in the 1950s to a peak of 18.5 from 1970 to 1974. From this peak, the incidence significantly declined to 6.2 per 100,000 person-years by the early-1990s and reached a nadir of 3.2 from 2015 to 2017 (p
Source: Otology and Neurotology - Category: ENT & OMF Tags: OTOSCLEROSIS Source Type: research