Tim-3 Expression and MGMT Methylation Status Association With Survival in Glioblastoma

ConclusionsWe profiled the immune status of MGMT promoter methylation in GBM and established a local immune signature for GBM that could independently identify patients with a favorable prognosis, indicating a relationship between prognosis and GBM immune signature. MGMT promoter methylation with lower Tim-3 expression was significantly associated with better survival.
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research