Effect of disease ‐modifying agents and their association with mortality in multi‐morbid patients with heart failure with reduced ejection fraction

ConclusionsHigher doses of beta ‐adrenoceptor antagonist are associated with greater protection from sudden death, most evident in multi‐morbid patients. Patients with COPD who appear to be at the highest risk of sudden death are prescribed the lowest doses and less likely to be implanted with implantable cardioverter defibril lators, which might represent a missed opportunity to optimize safe and proven therapies for these patients.

Source: ESC Heart Failure - September 12, 2020 Category: Cardiology Authors: Sam Straw, Melanie McGinlay, Samuel D. Relton, Aaron O. Koshy, John Gierula, Maria F. Paton, Michael Drozd, Judith E Lowry, Charlotte Cole, Richard M Cubbon, Klaus K. Witte, Mark T. Kearney Tags: Original Research Article Source Type: research