Evidence for maternal diet-mediated effects on the offspring microbiome and immunity: implications for public health initiatives.

Evidence for maternal diet-mediated effects on the offspring microbiome and immunity: implications for public health initiatives. Pediatr Res. 2020 Sep 12;: Authors: Mirpuri J Abstract Diets rich in saturated fats have become a staple globally. Fifty percent of women of childbearing age in the United States are obese or overweight, with diet being a significant contributor. There is increasing evidence of the impact of maternal high-fat diet on the offspring microbiome. Alterations of the neonatal microbiome have been shown to be associated with multiple morbidities, including the development of necrotizing enterocolitis, atopy, asthma, metabolic dysfunction, and hypertension among others. This review provides an overview of the recent studies and mechanisms being examined on how maternal diet can alter the immune response and microbiome in offspring and the implications for directed public health initiatives for women of childbearing age. IMPACT: Maternal diet is important in shaping the offspring microbiome and neonatal immune system.Reviews the current literature in the field and suggests potential mechanisms and areas of research to be targeted.Highlights the current scope of our knowledge of ideal nutrition during pregnancy and consideration for enhanced public health initiatives to promote well-being of the future generation.Fig. 1POTENTIAL MECHANISMS FOR MATERNAL DIET-MEDIATED EFFECTS ON THE FETUS AFFECTING POSTNATAL COLONIZATION AND IMMUNITY.: a ...
Source: Pediatric Research - Category: Pediatrics Authors: Tags: Pediatr Res Source Type: research

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Source: OnMedica Latest News - Category: UK Health Source Type: news
Conclusion: Although some argue that abortion is detrimental to women's health, these study data indicate that physical health is no worse in women who sought and underwent abortion than in women who were denied abortion. Indeed, differences emerged suggesting worse health among those who gave birth. Primary Funding Source: An anonymous foundation. PMID: 31181576 [PubMed - as supplied by publisher]
Source: Annals of Internal Medicine - Category: Internal Medicine Authors: Tags: Ann Intern Med Source Type: research
CONCLUSIONS: Among women of childbearing ages, asthma burden varies across demographic and clinical characteristics and has increased in recent years. PMID: 31014137 [PubMed - as supplied by publisher]
Source: Journal of Asthma - Category: Respiratory Medicine Tags: J Asthma Source Type: research
Conditions:   Gestational Diabetes Mellitus in Pregnancy;   Gestational Hypertension;   Thyroid Disease Pregnancy;   Obesity;   Anemia in Pregnancy;   Complications, Pregnancy;   Depression;   Obstetric Labor Complications;   Asthma;   Allergic Disorder;   Immune System Diseases;   N eurodevelopmental Disorders;   Reproductive Disorder Intervention:   Other: No intervention Sponsors:   Sun Yat-sen University;   Huizhou First Maternal and Chi...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
The objective of the study was to explore trial of labor and its failure in pregnancies with medical risk conditions, in a population with a high trial of labor rate.Material and methodsIn a cohort study (n=57  109), using data from the Medical Birth Registry of Norway 1989‐2014, women with a second delivery after a first pregnancy cesarean section were included. Preterm, multiple, and non‐cephalic deliveries were excluded. The outcomes were trial of labor and failed trial of labor, assessed as rates and relative risk, using deliveries without risk conditions as reference. Temporal trends were assessed by three‐...
Source: Acta Obstetricia et Gynecologica Scandinavica - Category: OBGYN Authors: Tags: Original Research Article Source Type: research
zer The aim of this study was to assess the association between lifetime spousal violence victimization, spousal violence perpetration, and physical health outcomes and behaviours among women in India. In the 2015–2016 National Family Health Survey, a sample of ever-married women (15–49 years) (N = 66,013) were interviewed about spousal violence. Results indicate that 29.9% of women reported lifetime spousal physical violence victimization and 7.1% lifetime spousal sexual violence victimization (31.1% physical and/or sexual violence victimization), and 3.5% lifetime spousal physical violence perpetr...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
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