Outcomes of metabolic surgery in obese patients with type 2 diabetes with respect to impact on beta cell function, insulin sensitivity and diabetes remission - A study from south India

Publication date: Available online 12 September 2020Source: Diabetes &Metabolic Syndrome: Clinical Research &ReviewsAuthor(s): Sundaramoorthy Chandru, Thyparambil Aravindakshan Pramodkumar, Rajendra Pradeepa, Subramaniapillai Muthukumar, Muthuswamy Balasubramanyam, Raghavan Bhuvaneshwari, Ranjit Mohan Anjana, Viswanathan Mohan
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research

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MAGMA. 2021 Aug 2. doi: 10.1007/s10334-021-00946-9. Online ahead of print.ABSTRACTBACKGROUND: There is increasing appreciation of the association of obesity beyond co-morbidities, such as cancers, Type 2 diabetes, hypertension, and stroke to also impact upon the muscle to give rise to sarcopenic obesity. Phenotypic knowledge of obesity is crucial for profiling and management of obesity, as different fat-subcutaneous adipose tissue depots (SAT) and visceral adipose tissue depots (VAT) have various degrees of influence on metabolic syndrome and morbidities. Manual segmentation is time consuming and laborious. Study focuses o...
Source: Magma - Category: Radiology Authors: Source Type: research
We present a broad overview of novel insights linking cardiovascular derangements and CKD with a focus on metabolic disorders affecting PRAT. We also argue that the confluence among these pathways may open several perspectives for future pharmacological therapies against CKD and CVD possibly by modulating PRAT immunometabolism.
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research
Several studies have demonstrated suppressed levels of acylated (AG) and unacylated ghrelin (UAG) in patients with type 2 diabetes. However, the role of these hormones in type 1 diabetes has not been extensive...
Source: Diabetology and Metabolic Syndrome - Category: Endocrinology Authors: Tags: Research Source Type: research
Been lean individuals would not insure that a healthy metabolic profile. The study confirmed that lean individuals especially in the context of fatty liver disease have a metabolic profile close to the obese general population. Lean NAFLD has a metabolic profile with dysmetabolic findings of impaired glycosylated hemoglobin and elevated lipid profile panel. AbstractNon-alcoholic liver disease (NAFLD) is a metabolic liver disease associated with visceral adiposity and insulin resistance. Recently, NAFLD has been described in lean individuals who additionally have impaired metabolic parameters similar to their non-lean count...
Source: Physiological Reports - Category: Physiology Authors: Tags: ORIGINAL ARTICLE Source Type: research
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research
ABSTRACTAimsTo compare glycemic control one-year after treatment in patients with mildly obese (BMI 27.5-34.9 kg/m2) type 2 diabetes mellitus (T2DM) who underwent bariatric surgery (BS) to those who received medical treatment (MT) in Japan.Materials and MethodsA retrospective study using real world data was conducted in electronic medical records from a tertiary care hospital and in JMDC Inc. (JMDC) claim database from 2008 to 2019. Each patient was propensity score-matched between the BS and the MT group by age, gender, BMI, HbA1c, and T2DM duration and compared from the index date to the one-year post-index.ResultsThe st...
Source: Journal of Diabetes Investigation - Category: Endocrinology Authors: Tags: ORIGINAL ARTICLE Source Type: research
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research
CONCLUSIONS: Tai Chi may be effective for enhancing the physiological and psychosocial wellbeing of community-dwelling adults at risk of MetS. Further RCTs are needed to examine its effects in adults with MetS and identify optimal regimes.PMID:34260997 | DOI:10.1016/j.ctcp.2021.101445
Source: Complementary Therapies in Clinical Practice - Category: Complementary Medicine Authors: Source Type: research
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