Modulating the physicochemical and biological properties of carbon dots synthesised from plastic waste for effective sensing of E. coli.

Modulating the physicochemical and biological properties of carbon dots synthesised from plastic waste for effective sensing of E. coli. Colloids Surf B Biointerfaces. 2020 Sep 01;196:111333 Authors: Kumari M, Chaudhary S Abstract The reliable means for the quick recognition of pathogenic bacteria for disease prevention has acquired a considerable significance among researchers for human wellbeing. The purpose of current study is to fabricate highly photo-luminescent and biocompatible carbon dots (CQDs) from single used plastic waste such as poly bags, cups and bottles for selective sensing of E. coli. The formed small sized spherical CQDs have possessed high water solubility with excellent photo stable nature. The detailed fluorescence emission studies of CQDs have illustrated the overview of different types of surface defects and emissive states in formed particles. In addition, the specific role of prepared CQDs with bio-compatible nature has been thoroughly checked on hemolysis of red blood cells by employing in-vitro blood compatibility assay. A combination of anticoagulant and thrombolytic activity of CQDs with anti-oxidative activities from reactive oxygen species (ROS) generation were found to be responsible for the biocompatibility of formed CQDs. The effective in vitro stability toward histidine, cysteine, bovine serum albumin (BSA), human serum albumin (HSA) and saline supported the biocompatibility of formed particles as ...
Source: Colloids and Surfaces - Category: Biotechnology Authors: Tags: Colloids Surf B Biointerfaces Source Type: research