[Hyperfibrinolysis after Resuscitation due to Acute Pulmonary Artery Embolism].

[Hyperfibrinolysis after Resuscitation due to Acute Pulmonary Artery Embolism].
Anasthesiol Intensivmed Notfallmed Schmerzther. 2020 Sep;55(9):569-575
Authors: Weber CF, Wesselly A, Held T, Anheuser P, Schönwälder J, Weischer W
Abstract
In an 81-year-old patient, acute hemodynamic instability requiring resuscitation occurred during an elective transurethral prostate resection. The procedure was ended prematurely and after ROSC a CT diagnosis was carried out, which confirmed the suspected diagnosis of fulminant pulmonary embolism. Anticoagulant therapy with heparin was initiated. About two hours after admission to the intensive care unit, hemorrhage requiring massive transfusion developed, which according to viscoelastometric diagnostics was most likely due to fulminant hyperfibrinolysis. This case report describes the pathophysiology of so-called post-cardiac arrest coagulopathy and discusses the use of antifibrinolytic therapy in patients with thrombotic complications such as pulmonary artery embolism.
PMID: 32916740 [PubMed - as supplied by publisher]

Source: Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS - August 31, 2020 Category: Intensive Care Authors: Weber CF, Wesselly A, Held T, Anheuser P, Schönwälder J, Weischer W Tags: Anasthesiol Intensivmed Notfallmed Schmerzther Source Type: research