Biologics for the Treatments of Allergic Conditions

By selectively targeting specific steps of the immune inflammation cascade, biologic drugs for severe asthma have substantially contributed to increase the standard of care, to reduce drug-related morbidity. and most importantly to ameliorate patients ’ quality of life. Upcoming molecules are going to provide a chance for severe phenotypes besides Th2 high through the interaction with epithelial and innate immunity. Some practical aspects including optimal treatment duration, the possibility of a dose treatment modulation, the place and relevan ce of ICS in best responders are still under debate. Long-term safety, especially when interacting with innate immunity needs to be further investigated.
Source: Immunology and Allergy Clinics of North America - Category: Allergy & Immunology Authors: Source Type: research