Betaine and choline status modify the effects of folic acid and creatine supplementation on arsenic methylation in a randomized controlled trial of Bangladeshi adults

ConclusionsEffects of FA and creatine supplementation on arsenic methylation capacity were greater among individuals with low betaine and choline status, respectively. The efficacy of FA and creatine interventions to facilitate arsenic methylation may be modified by choline and betaine nutritional status.Clinical trial registrationClinical Trial Registry Identifier: NCT01050556, U.S. National Library of Medicine,https://clinicaltrials.gov; registered January 15, 2010.
Source: European Journal of Nutrition - Category: Nutrition Source Type: research