Quercetin and cervical cancer: a view of great scope

AbstractCervical cancer (CC) is the most common gynecological cancer and is one of the results of high-risk HPV infection. Recent statistics demonstrate that 90% of cervical cancer cases are diagnosed in low- and middle-income countries. These results are observed due to the poor sanitation and lack of proper preventive strategies. Quercetin is a plant compound with a great number of beneficial properties which increasing the level of sanitation or acting as a preventive agent are not of its capabilities; however, what quercetin is capable of is preventing the cancer from progression in CC patients. Cell proliferation, growth, viability, survival, and migration are just a limited number of cellular processes which are prone to be affected by quercetin. In this review, we have considered each distinct role of quercetin on cellular and molecular processes, occurring as a consequence of becoming cancerous, in the cells of uterine cervix. We look forward to attract the attention of scientific community to this marvelous agent in order to help CC patients from taking expensive, toxic, and risky common therapeutic methods used for treating early to metastatic cervical cancer.
Source: Medicinal Chemistry Research - Category: Chemistry Source Type: research